NFL GameDay 2001 is a simulation, sports game in which players can control and manage football teams, engaging in realistic gameplay and strategic decision-making. In this game, players experience the NFL season with lifelike player graphics, commentary by Dick Enberg and Phil Simms, and advanced control features such as total-control passing and running, allowing for precise gameplay and strategic plays. It stands out with its realistic graphics, enhanced play editing tools, and a comprehensive general manager mode that simplifies drafting and team management, providing an immersive football simulation experience.