The Lost Cases of Sherlock Holmes 2 is a single-player casual puzzle game in which players take on the role of Sherlock Holmes to investigate and solve a series of mysterious crimes. In this game, players return to 221 Baker Street and explore Victorian England, solving 16 intricate cases by gathering evidence and analyzing clues across 60 detailed locations including Stonehenge, Marlsbury Castle, and London's Music Hall. It stands out with its rich variety of gameplay elements, including over 50 puzzles such as anagrams and cryptograms, as well as more than 40 levels of hidden object and find-the-difference challenges, featuring a cast of over 100 characters like Watson, Mycroft, and Inspector Lestrade, all set within a compelling mystery theme.